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Structural and functional insights into esterase-mediated macrolide resistance

Macrolides are a class of antibiotics widely used in both medicine and agriculture. Unsurprisingly, as a consequence of their exensive usage a plethora of resistance mechanisms have been encountered in pathogenic bacteria. One of these resistance mechanisms entails the enzymatic cleavage of the macr...

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Detalles Bibliográficos
Autores principales: Zieliński, Michał, Park, Jaeok, Sleno, Barry, Berghuis, Albert M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7979712/
https://www.ncbi.nlm.nih.gov/pubmed/33741980
http://dx.doi.org/10.1038/s41467-021-22016-3