Citrullination of pyruvate kinase M2 by PADI1 and PADI3 regulates glycolysis and cancer cell proliferation

Chromodomain helicase DNA binding protein 4 (CHD4) is an ATPase subunit of the Nucleosome Remodelling and Deacetylation (NuRD) complex that regulates gene expression. CHD4 is essential for growth of multiple patient derived melanoma xenografts and for breast cancer. Here we show that CHD4 regulates...

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Detalles Bibliográficos
Autores principales: Coassolo, Sébastien, Davidson, Guillaume, Negroni, Luc, Gambi, Giovanni, Daujat, Sylvain, Romier, Christophe, Davidson, Irwin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7979715/
https://www.ncbi.nlm.nih.gov/pubmed/33741961
http://dx.doi.org/10.1038/s41467-021-21960-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7979715/
https://www.ncbi.nlm.nih.gov/pubmed/33741961
http://dx.doi.org/10.1038/s41467-021-21960-4

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