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Citrullination of pyruvate kinase M2 by PADI1 and PADI3 regulates glycolysis and cancer cell proliferation
Chromodomain helicase DNA binding protein 4 (CHD4) is an ATPase subunit of the Nucleosome Remodelling and Deacetylation (NuRD) complex that regulates gene expression. CHD4 is essential for growth of multiple patient derived melanoma xenografts and for breast cancer. Here we show that CHD4 regulates...
Autores principales: | Coassolo, Sébastien, Davidson, Guillaume, Negroni, Luc, Gambi, Giovanni, Daujat, Sylvain, Romier, Christophe, Davidson, Irwin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7979715/ https://www.ncbi.nlm.nih.gov/pubmed/33741961 http://dx.doi.org/10.1038/s41467-021-21960-4 |
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