Melanoma subpopulations that rapidly escape MAPK pathway inhibition incur DNA damage and rely on stress signalling

Despite the increasing number of effective anti-cancer therapies, successful treatment is limited by the development of drug resistance. While the contribution of genetic factors to drug resistance is undeniable, little is known about how drug-sensitive cells first evade drug action to proliferate i...

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Detalles Bibliográficos
Autores principales: Yang, Chen, Tian, Chengzhe, Hoffman, Timothy E., Jacobsen, Nicole K., Spencer, Sabrina L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7979728/
https://www.ncbi.nlm.nih.gov/pubmed/33741929
http://dx.doi.org/10.1038/s41467-021-21549-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7979728/
https://www.ncbi.nlm.nih.gov/pubmed/33741929
http://dx.doi.org/10.1038/s41467-021-21549-x

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