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FTO-mediated cytoplasmic m(6)A(m) demethylation adjusts stem-like properties in colorectal cancer cell

Cancer stem cells (CSCs) are a small but critical cell population for cancer biology since they display inherent resistance to standard therapies and give rise to metastases. Despite accruing evidence establishing a link between deregulation of epitranscriptome-related players and tumorigenic proces...

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Detalles Bibliográficos
Autores principales: Relier, Sébastien, Ripoll, Julie, Guillorit, Hélène, Amalric, Amandine, Achour, Cyrinne, Boissière, Florence, Vialaret, Jérôme, Attina, Aurore, Debart, Françoise, Choquet, Armelle, Macari, Françoise, Marchand, Virginie, Motorin, Yuri, Samalin, Emmanuelle, Vasseur, Jean-Jacques, Pannequin, Julie, Aguilo, Francesca, Lopez-Crapez, Evelyne, Hirtz, Christophe, Rivals, Eric, Bastide, Amandine, David, Alexandre
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7979729/
https://www.ncbi.nlm.nih.gov/pubmed/33741917
http://dx.doi.org/10.1038/s41467-021-21758-4