Cargando…

FTO-mediated cytoplasmic m(6)A(m) demethylation adjusts stem-like properties in colorectal cancer cell

Cancer stem cells (CSCs) are a small but critical cell population for cancer biology since they display inherent resistance to standard therapies and give rise to metastases. Despite accruing evidence establishing a link between deregulation of epitranscriptome-related players and tumorigenic proces...

Descripción completa

Detalles Bibliográficos
Autores principales:	Relier, Sébastien, Ripoll, Julie, Guillorit, Hélène, Amalric, Amandine, Achour, Cyrinne, Boissière, Florence, Vialaret, Jérôme, Attina, Aurore, Debart, Françoise, Choquet, Armelle, Macari, Françoise, Marchand, Virginie, Motorin, Yuri, Samalin, Emmanuelle, Vasseur, Jean-Jacques, Pannequin, Julie, Aguilo, Francesca, Lopez-Crapez, Evelyne, Hirtz, Christophe, Rivals, Eric, Bastide, Amandine, David, Alexandre
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7979729/ https://www.ncbi.nlm.nih.gov/pubmed/33741917 http://dx.doi.org/10.1038/s41467-021-21758-4

Ejemplares similares

Antibiotics inhibit sphere-forming ability in suspension culture
por: Relier, Sébastien, et al.
Publicado: (2016)

Multivariate Analysis of RNA Chemistry Marks Uncovers Epitranscriptomics-Based Biomarker Signature for Adult Diffuse Glioma Diagnostics
por: Relier, S., et al.
Publicado: (2022)

Interaction of rRNA with mRNA and tRNA in Translating Mammalian Ribosome: Functional Implications in Health and Disease
por: Bastide, Amandine, et al.
Publicado: (2018)

mRNA maturation in giant viruses: variation on a theme
por: Priet, Stéphane, et al.
Publicado: (2015)

METTL3 regulates breast cancer-associated alternative splicing switches
por: Achour, Cyrinne, et al.
Publicado: (2023)

The multifaceted functions of the Fat mass and Obesity-associated protein (FTO) in normal and cancer cells
por: Relier, Sébastien, et al.
Publicado: (2022)

La-related protein 1 (LARP1) repression of TOP mRNA translation is mediated through its cap-binding domain and controlled by an adjacent regulatory region
por: Philippe, Lucas, et al.
Publicado: (2018)

La-related protein 1 (LARP1) repression of TOP mRNA translation is mediated through its cap-binding domain and controlled by an adjacent regulatory region
por: Philippe, Lucas, et al.
Publicado: (2020)

The ribosome, (slow) beating heart of cancer (stem) cell
por: Bastide, Amandine, et al.
Publicado: (2018)

Readthrough isoform of aquaporin-4 (AQP4) as a therapeutic target for Alzheimer’s disease and other proteinopathies
por: Mohaupt, Pablo, et al.
Publicado: (2023)

Stimuli-responsive oligonucleotides in prodrug-based approaches for gene silencing
por: Debart, Françoise, et al.
Publicado: (2018)

Regulation of mRNA Trafficking by Nuclear Pore Complexes
por: Bonnet, Amandine, et al.
Publicado: (2014)

CD44v6 Defines a New Population of Circulating Tumor Cells Not Expressing EpCAM
por: Belthier, Guillaume, et al.
Publicado: (2021)

From radioimmunoassay to mass spectrometry: a new method to quantify orexin-A (hypocretin-1) in cerebrospinal fluid
por: Hirtz, Christophe, et al.
Publicado: (2016)

The alternative proteome in neurobiology
por: Mohaupt, Pablo, et al.
Publicado: (2022)

The Non-Coding RNA Journal Club: Highlights on Recent Papers—5
por: Achour, Cyrinne, et al.
Publicado: (2017)

Proteomics Challenges for the Assessment of Synuclein Proteoforms as Clinical Biomarkers in Parkinson’s Disease
por: Pons, Marie-Laure, et al.
Publicado: (2022)

β-Synuclein as a candidate blood biomarker for synaptic degeneration in Alzheimer’s disease
por: Mohaupt, Pablo, et al.
Publicado: (2022)

Physical modeling of ribosomes along messenger RNA: Estimating kinetic parameters from ribosome profiling experiments using a ballistic model
por: Chevalier, Carole, et al.
Publicado: (2023)

The stability of Fbw7α in M-phase requires its phosphorylation by PKC
por: Zitouni, Sihem, et al.
Publicado: (2017)

Chance Fluctuations in mRNA Output in Mammalian Cells
por: Chanut, Françoise
Publicado: (2006)

Ginkgo biloba extract increases neurite outgrowth and activates the Akt/mTOR pathway
por: Lejri, Imane, et al.
Publicado: (2019)

A Model for World-Class 10,000 m Running Performances: Strategy and Optimization
por: Mercier, Quentin, et al.
Publicado: (2021)

Conjugation of Doxorubicin to siRNA Through Disulfide-based Self-immolative Linkers
por: Gauthier, Florian, et al.
Publicado: (2020)

Dynamic association of human mRNP proteins with mitochondrial tRNAs in the cytosol
por: Jády, Beáta E., et al.
Publicado: (2018)

Antibody-free quantification of seven tau peptides in human CSF using targeted mass spectrometry
por: Bros, Pauline, et al.
Publicado: (2015)

The m(6)A pathway protects the transcriptome integrity by restricting RNA chimera formation in plants
por: Pontier, Dominique, et al.
Publicado: (2019)

An Objective Structured Clinical Examination (OSCE) for French Dental Students: Feedback after 2 Years
por: Egloff-Juras, Claire, et al.
Publicado: (2021)

Cap-proximal nucleotides via differential eIF4E binding and alternative promoter usage mediate translational response to energy stress
por: Tamarkin-Ben-Harush, Ana, et al.
Publicado: (2017)

An epitranscriptomic mechanism underlies selective mRNA translation remodelling in melanoma persister cells
por: Shen, Shensi, et al.
Publicado: (2019)

Synthesis of point-modified mRNA
por: Hertler, Jasmin, et al.
Publicado: (2022)

Squalene-based multidrug nanoparticles for improved mitigation of uncontrolled inflammation in rodents
por: Dormont, Flavio, et al.
Publicado: (2020)

Relevance of sensitization to legumes in peanut‐allergic children
por: Muller, Timé, et al.
Publicado: (2022)

Journées S.M.F.
por: Colliot-Thélène, Jean-Louis, et al.
Publicado: (1982)

Sequence analysis of two alleles reveals that intra-and intergenic recombination played a role in the evolution of the radish fertility restorer (Rfo)
por: Hernandez Mora, José R, et al.
Publicado: (2010)

Translational reprogramming of colorectal cancer cells induced by 5-fluorouracil through a miRNA-dependent mechanism
por: Bash-Imam, Zeina, et al.
Publicado: (2017)

Data from a targeted proteomics approach to discover biomarkers in saliva for the clinical diagnosis of periodontitis
por: Orti, V., et al.
Publicado: (2018)

Sox9 regulates cell proliferation and is required for Paneth cell differentiation in the intestinal epithelium
por: Bastide, Pauline, et al.
Publicado: (2007)

An upstream open reading frame within an IRES controls expression of a specific VEGF-A isoform
por: Bastide, Amandine, et al.
Publicado: (2008)

Three-Year Breeding Cycle of Rainbow Trout (Oncorhynchus mykiss) Fed a Plant-Based Diet, Totally Free of Marine Resources: Consequences for Reproduction, Fatty Acid Composition and Progeny Survival
por: Lazzarotto, Viviana, et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_hpb3qnkeqeqqgumfa7k2b8dml8