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Complete response to PD-1 blockade following EBV-specific T-cell therapy in metastatic nasopharyngeal carcinoma

Nasopharyngeal carcinoma (NPC) is an Epstein–Barr virus (EBV)-associated heterogeneous disease and is characterized by peritumoral immune infiltrate. Adoptive T-cell therapy (ACT) has emerged as a potential therapeutic strategy for NPC. However, the tumor microenvironment remains a major roadblock f...

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Detalles Bibliográficos
Autores principales: Smith, Corey, McGrath, Margaret, Neller, Michelle A., Matthews, Katherine K., Crooks, Pauline, Le Texier, Laetitia, Panizza, Benedict, Porceddu, Sandro, Khanna, Rajiv
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7979738/
https://www.ncbi.nlm.nih.gov/pubmed/33742086
http://dx.doi.org/10.1038/s41698-021-00162-7