Structural basis of the dynamic human CEACAM1 monomer-dimer equilibrium

Human (h) carcinoembryonic antigen-related cell adhesion molecule 1 (CEACAM1) function depends upon IgV-mediated homodimerization or heterodimerization with host ligands, including hCEACAM5, hTIM-3, PD-1, and a variety of microbial pathogens. However, there is little structural information available...

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Detalles Bibliográficos
Autores principales: Gandhi, Amit K., Sun, Zhen-Yu J., Kim, Walter M., Huang, Yu-Hwa, Kondo, Yasuyuki, Bonsor, Daniel A., Sundberg, Eric J., Wagner, Gerhard, Kuchroo, Vijay K., Petsko, Gregory A., Blumberg, Richard S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7979749/
https://www.ncbi.nlm.nih.gov/pubmed/33742094
http://dx.doi.org/10.1038/s42003-021-01871-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7979749/
https://www.ncbi.nlm.nih.gov/pubmed/33742094
http://dx.doi.org/10.1038/s42003-021-01871-2

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