Molecular basis of V-ATPase inhibition by bafilomycin A1

Pharmacological inhibition of vacuolar-type H(+)-ATPase (V-ATPase) by its specific inhibitor can abrogate tumor metastasis, prevent autophagy, and reduce cellular signaling responses. Bafilomycin A1, a member of macrolide antibiotics and an autophagy inhibitor, serves as a specific and potent V-ATPa...

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Detalles Bibliográficos
Autores principales: Wang, Rong, Wang, Jin, Hassan, Abdirahman, Lee, Chia-Hsueh, Xie, Xiao-Song, Li, Xiaochun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7979754/
https://www.ncbi.nlm.nih.gov/pubmed/33741963
http://dx.doi.org/10.1038/s41467-021-22111-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7979754/
https://www.ncbi.nlm.nih.gov/pubmed/33741963
http://dx.doi.org/10.1038/s41467-021-22111-5

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