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Molecular basis of V-ATPase inhibition by bafilomycin A1
Pharmacological inhibition of vacuolar-type H(+)-ATPase (V-ATPase) by its specific inhibitor can abrogate tumor metastasis, prevent autophagy, and reduce cellular signaling responses. Bafilomycin A1, a member of macrolide antibiotics and an autophagy inhibitor, serves as a specific and potent V-ATPa...
Autores principales: | Wang, Rong, Wang, Jin, Hassan, Abdirahman, Lee, Chia-Hsueh, Xie, Xiao-Song, Li, Xiaochun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7979754/ https://www.ncbi.nlm.nih.gov/pubmed/33741963 http://dx.doi.org/10.1038/s41467-021-22111-5 |
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