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Spatiotemporal single-cell RNA sequencing of developing chicken hearts identifies interplay between cellular differentiation and morphogenesis

Single-cell RNA sequencing is a powerful tool to study developmental biology but does not preserve spatial information about tissue morphology and cellular interactions. Here, we combine single-cell and spatial transcriptomics with algorithms for data integration to study the development of the chic...

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Detalles Bibliográficos
Autores principales: Mantri, Madhav, Scuderi, Gaetano J., Abedini-Nassab, Roozbeh, Wang, Michael F. Z., McKellar, David, Shi, Hao, Grodner, Benjamin, Butcher, Jonathan T., De Vlaminck, Iwijn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7979764/
https://www.ncbi.nlm.nih.gov/pubmed/33741943
http://dx.doi.org/10.1038/s41467-021-21892-z