Deep generative neural network for accurate drug response imputation

Drug response differs substantially in cancer patients due to inter- and intra-tumor heterogeneity. Particularly, transcriptome context, especially tumor microenvironment, has been shown playing a significant role in shaping the actual treatment outcome. In this study, we develop a deep variational...

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Detalles Bibliográficos
Autores principales: Jia, Peilin, Hu, Ruifeng, Pei, Guangsheng, Dai, Yulin, Wang, Yin-Ying, Zhao, Zhongming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7979803/
https://www.ncbi.nlm.nih.gov/pubmed/33741950
http://dx.doi.org/10.1038/s41467-021-21997-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7979803/
https://www.ncbi.nlm.nih.gov/pubmed/33741950
http://dx.doi.org/10.1038/s41467-021-21997-5

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