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CAP2 is a regulator of actin pointed end dynamics and myofibrillogenesis in cardiac muscle

The precise assembly of actin-based thin filaments is crucial for muscle contraction. Dysregulation of actin dynamics at thin filament pointed ends results in skeletal and cardiac myopathies. Here, we discovered adenylyl cyclase-associated protein 2 (CAP2) as a unique component of thin filament poin...

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Detalles Bibliográficos
Autores principales: Colpan, Mert, Iwanski, Jessika, Gregorio, Carol C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7979805/
https://www.ncbi.nlm.nih.gov/pubmed/33742108
http://dx.doi.org/10.1038/s42003-021-01893-w