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CAP2 is a regulator of actin pointed end dynamics and myofibrillogenesis in cardiac muscle
The precise assembly of actin-based thin filaments is crucial for muscle contraction. Dysregulation of actin dynamics at thin filament pointed ends results in skeletal and cardiac myopathies. Here, we discovered adenylyl cyclase-associated protein 2 (CAP2) as a unique component of thin filament poin...
Autores principales: | Colpan, Mert, Iwanski, Jessika, Gregorio, Carol C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7979805/ https://www.ncbi.nlm.nih.gov/pubmed/33742108 http://dx.doi.org/10.1038/s42003-021-01893-w |
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