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A computational workflow for the expansion of heterologous biosynthetic pathways to natural product derivatives

Plant natural products (PNPs) and their derivatives are important but underexplored sources of pharmaceutical molecules. To access this untapped potential, the reconstitution of heterologous PNP biosynthesis pathways in engineered microbes provides a valuable starting point to explore and produce no...

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Detalles Bibliográficos
Autores principales: Hafner, Jasmin, Payne, James, MohammadiPeyhani, Homa, Hatzimanikatis, Vassily, Smolke, Christina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7979880/
https://www.ncbi.nlm.nih.gov/pubmed/33741955
http://dx.doi.org/10.1038/s41467-021-22022-5