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Contributions of lipopolysaccharide and the type IVB secretion system to Coxiella burnetii vaccine efficacy and reactogenicity

Coxiella burnetii is the bacterial causative agent of the zoonosis Q fever. The current human Q fever vaccine, Q-VAX(®), is a fixed, whole cell vaccine (WCV) licensed solely for use in Australia. C. burnetii WCV administration is associated with a dermal hypersensitivity reaction in people with pre-...

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Detalles Bibliográficos
Autores principales: Long, Carrie M., Beare, Paul A., Cockrell, Diane C., Fintzi, Jonathan, Tesfamariam, Mahelat, Shaia, Carl I., Heinzen, Robert A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7979919/
https://www.ncbi.nlm.nih.gov/pubmed/33741986
http://dx.doi.org/10.1038/s41541-021-00296-6