Cargando…

R-loop resolution promotes co-transcriptional chromatin silencing

RNA-mediated chromatin silencing is central to genome regulation in many organisms. However, how nascent non-coding transcripts regulate chromatin is poorly understood. Here, through analysis of Arabidopsis FLC, we show that resolution of a nascent-transcript-induced R-loop promotes chromatin silenc...

Descripción completa

Detalles Bibliográficos
Autores principales:	Xu, Congyao, Wu, Zhe, Duan, Hong-Chao, Fang, Xiaofeng, Jia, Guifang, Dean, Caroline
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7979926/ https://www.ncbi.nlm.nih.gov/pubmed/33741984 http://dx.doi.org/10.1038/s41467-021-22083-6

Ejemplares similares

Antagonistic cotranscriptional regulation through ARGONAUTE1 and the THO/TREX complex orchestrates FLC transcriptional output
por: Xu, Congyao, et al.
Publicado: (2021)

TDRD3 promotes DHX9 chromatin recruitment and R-loop resolution
por: Yuan, Wei, et al.
Publicado: (2021)

Increased chromatin accessibility promotes the evolution of a transcriptional silencer in Drosophila
por: Ling, Liucong, et al.
Publicado: (2023)

The 3′ processing of antisense RNAs physically links to chromatin-based transcriptional control
por: Fang, Xiaofeng, et al.
Publicado: (2020)

Role of Ldb1 in the transition from chromatin looping to transcription activation
por: Krivega, Ivan, et al.
Publicado: (2013)

Role of LDB1 in the transition from chromatin looping to transcription activation
por: Krivega, Ivan, et al.
Publicado: (2014)

The anatomy of transcriptionally active chromatin loops in Drosophila primary spermatocytes using super-resolution microscopy
por: Ball, Madeleine L., et al.
Publicado: (2023)

R-loops regulate promoter-proximal chromatin architecture and cellular differentiation
por: Chen, Poshen B., et al.
Publicado: (2015)

Minor Loops in Major Folds: Enhancer–Promoter Looping, Chromatin Restructuring, and Their Association with Transcriptional Regulation and Disease
por: Matharu, Navneet, et al.
Publicado: (2015)

PARP1 associates with R-loops to promote their resolution and genome stability
por: Laspata, Natalie, et al.
Publicado: (2023)

Transcription-coupled changes to chromatin underpin gene silencing by transcriptional interference
por: Ard, Ryan, et al.
Publicado: (2016)

DDX17 helicase promotes resolution of R-loop-mediated transcription–replication conflicts in human cells
por: Boleslavska, Barbora, et al.
Publicado: (2022)

Differential Interactions of the Autonomous Pathway RRM Proteins and Chromatin Regulators in the Silencing of Arabidopsis Targets
por: Bäurle, Isabel, et al.
Publicado: (2008)

Chromatin loop anchors predict transcript and exon usage
por: Zhang, Yu, et al.
Publicado: (2021)

Capture of associated targets on chromatin links long-distance chromatin looping to transcriptional coordination
por: Bourgo, Ryan J., et al.
Publicado: (2016)

Hypoosmotic stress induces R loop formation in nucleoli and ATR/ATM-dependent silencing of nucleolar transcription
por: Velichko, Artem K, et al.
Publicado: (2019)

Helicases in R-loop Formation and Resolution
por: Yang, Shizhuo, et al.
Publicado: (2023)

R-loop induced G-quadruplex in non-template promotes transcription by successive R-loop formation
por: Lee, Chun-Ying, et al.
Publicado: (2020)

The yeast and human FACT chromatin-reorganizing complexes solve R-loop-mediated transcription–replication conflicts
por: Herrera-Moyano, Emilia, et al.
Publicado: (2014)

Multi-scale phase separation by explosive percolation with single-chromatin loop resolution
por: Sengupta, Kaustav, et al.
Publicado: (2022)

Chromatin Loop Extrusion and Chromatin Unknotting
por: Racko, Dusan, et al.
Publicado: (2018)

Chromatin Loops as Allosteric Modulators of Enhancer-Promoter Interactions
por: Doyle, Boryana, et al.
Publicado: (2014)

R-Loops Promote Antisense Transcription across the Mammalian Genome
por: Tan-Wong, Sue Mei, et al.
Publicado: (2019)

The RNA-induced transcriptional silencing complex targets chromatin exclusively via interacting with nascent transcripts
por: Shimada, Yukiko, et al.
Publicado: (2016)

The intersection of DNA replication with antisense 3′ RNA processing in Arabidopsis FLC chromatin silencing
por: Baxter, Colette L., et al.
Publicado: (2021)

RNA Stabilizes Transcription-Dependent Chromatin Loops Induced By Nuclear Hormones
por: Pezone, Antonio, et al.
Publicado: (2019)

Transcription-dependent cohesin repositioning rewires chromatin loops in cellular senescence
por: Olan, Ioana, et al.
Publicado: (2020)

Transcription shapes 3D chromatin organization by interacting with loop extrusion
por: Banigan, Edward J., et al.
Publicado: (2023)

InferLoop: leveraging single-cell chromatin accessibility for the signal of chromatin loop
por: Zhang, Feng, et al.
Publicado: (2023)

Chromatin loops associated with active genes and heterochromatin shape rice genome architecture for transcriptional regulation
por: Zhao, Lun, et al.
Publicado: (2019)

Loopy Chromatin Brings Distant DNA to Bear on Silencing Promoter Genes
por: Hoff, Mary
Publicado: (2008)

Thrap3 promotes R-loop resolution via interaction with methylated DDX5
por: Kang, Hyun Je, et al.
Publicado: (2021)

Chromatin looping and eRNA transcription precede the transcriptional activation of gene in the β-globin locus
por: Kim, Yea Woon, et al.
Publicado: (2015)

R-loops Associated with Triplet Repeat Expansions Promote Gene Silencing in Friedreich Ataxia and Fragile X Syndrome
por: Groh, Matthias, et al.
Publicado: (2014)

Transcriptional Silencing of Transposons by Piwi and Maelstrom and Its Impact on Chromatin State and Gene Expression
por: Sienski, Grzegorz, et al.
Publicado: (2012)

Restriction of Retrotransposon Mobilization in Schizosaccharomyces pombe by Transcriptional Silencing and Higher-Order Chromatin Organization
por: Murton, Heather E., et al.
Publicado: (2016)

Chromatin, gene silencing and HIV latency
por: Mok, Hoi-Ping, et al.
Publicado: (2007)

A chromatin twist to silencing choice
por: Leslie, Mitch
Publicado: (2007)

Novel system uses probasin-based promoter, transcriptional silencers and amplification loop to induce high-level prostate expression
por: Woraratanadharm, Jan, et al.
Publicado: (2007)

HiCORE: Hi-C Analysis for Identification of Core Chromatin Looping Regions with Higher Resolution
por: Lee, Hongwoo, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_a8g38c6jt9f67gq1cjnqc1f2k8