Peripheral decarboxylase inhibitors paradoxically induce aromatic L-amino acid decarboxylase

Peripheral decarboxylase inhibitors (PDIs) prevent conversion of levodopa to dopamine in the blood by the enzyme aromatic L-amino acid decarboxylase (AADC). Alterations in enzyme activity may contribute to the required higher dosages of levodopa observed in many patients with Parkinson’s disease. We...

Descripción completa

Detalles Bibliográficos
Autores principales: van Rumund, Anouke, Pavelka, Lukas, Esselink, Rianne A. J., Geurtz, Ben P. M., Wevers, Ron A., Mollenhauer, Brit, Krüger, Rejko, Bloem, Bastiaan R., Verbeek, Marcel M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7979935/
https://www.ncbi.nlm.nih.gov/pubmed/33741988
http://dx.doi.org/10.1038/s41531-021-00172-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7979935/
https://www.ncbi.nlm.nih.gov/pubmed/33741988
http://dx.doi.org/10.1038/s41531-021-00172-z

Ejemplares similares