Modulating Ocular Surface Pain Through Neurokinin-1 Receptor Blockade

PURPOSE: The purpose of this study was to test the role of substance P (SP) and its receptor neurokinin 1 (NK1R) on ocular surface pain. METHODS: Eight-week-old C57BL6/N (wild type [WT]) and B6.Cg-Tac1tm1Bbm/J (TAC1-KO) male mice were used. 5 M NaCl was topically applied on the cornea, followed by t...

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Detalles Bibliográficos
Autores principales: Lasagni Vitar, Romina Mayra, Barbariga, Marco, Fonteyne, Philippe, Bignami, Fabio, Rama, Paolo, Ferrari, Giulio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2021
Materias:
Cornea
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7980039/
https://www.ncbi.nlm.nih.gov/pubmed/33729475
http://dx.doi.org/10.1167/iovs.62.3.26

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7980039/
https://www.ncbi.nlm.nih.gov/pubmed/33729475
http://dx.doi.org/10.1167/iovs.62.3.26

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