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The Long Non-Coding RNA HOTAIR Is a Critical Epigenetic Mediator of Angiogenesis in Diabetic Retinopathy

PURPOSE: Diabetic retinopathy (DR) remains a pressing issue worldwide. Abnormal angiogenesis is a distinct vascular lesion in DR, and research has established that vascular endothelial growth factor A (VEGF-A) is a primary mediator of such changes. However, limitations in current anti-VEGF therapies...

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Detalles Bibliográficos
Autores principales: Biswas, Saumik, Feng, Biao, Chen, Shali, Liu, Jieting, Aref-Eshghi, Erfan, Gonder, John, Ngo, Vy, Sadikovic, Bekim, Chakrabarti, Subrata
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7980040/
https://www.ncbi.nlm.nih.gov/pubmed/33724292
http://dx.doi.org/10.1167/iovs.62.3.20