Cargando…

Restoration of mGluR6 Localization Following AAV-Mediated Delivery in a Mouse Model of Congenital Stationary Night Blindness

PURPOSE: Complete congenital stationary night blindness (cCSNB) is an incurable inherited retinal disorder characterized by an ON-bipolar cell (ON-BC) defect. GRM6 mutations are the third most prevalent cause of cCSNB. The Grm6(−)(/)(−) mouse model mimics the human phenotype, showing no b-wave in th...

Descripción completa

Detalles Bibliográficos
Autores principales:	Varin, Juliette, Bouzidi, Nassima, Dias, Miguel Miranda De Sousa, Pugliese, Thomas, Michiels, Christelle, Robert, Camille, Desrosiers, Melissa, Sahel, José-Alain, Audo, Isabelle, Dalkara, Deniz, Zeitz, Christina
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Association for Research in Vision and Ophthalmology 2021
Materias:	Visual Neuroscience
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7980044/ https://www.ncbi.nlm.nih.gov/pubmed/33729473 http://dx.doi.org/10.1167/iovs.62.3.24

Ejemplares similares

Substantial restoration of night vision in adult mice with congenital stationary night blindness
por: Varin, Juliette, et al.
Publicado: (2021)

A New Mouse Model for Complete Congenital Stationary Night Blindness Due to Gpr179 Deficiency
por: Orhan, Elise, et al.
Publicado: (2021)

A Novel Heterozygous Missense Mutation in GNAT1 Leads to Autosomal Dominant Riggs Type of Congenital Stationary Night Blindness
por: Zeitz, Christina, et al.
Publicado: (2018)

Mice Lacking Gpr179 with Complete Congenital Stationary Night Blindness Are a Good Model for Myopia
por: Wilmet, Baptiste, et al.
Publicado: (2022)

Lrit3 Deficient Mouse (nob6): A Novel Model of Complete Congenital Stationary Night Blindness (cCSNB)
por: Neuillé, Marion, et al.
Publicado: (2014)

Identification and characterization of novel TRPM1 autoantibodies from serum of patients with melanoma-associated retinopathy
por: Varin, Juliette, et al.
Publicado: (2020)

Rescue of Defective Electroretinographic Responses in Dp71-Null Mice With AAV-Mediated Reexpression of Dp71
por: Barboni, Mirella Telles Salgueiro, et al.
Publicado: (2020)

LRIT3 Differentially Affects Connectivity and Synaptic Transmission of Cones to ON- and OFF-Bipolar Cells
por: Neuillé, Marion, et al.
Publicado: (2017)

Molecular profiling of complete congenital stationary night blindness: A pilot study on an Indian cohort
por: Malaichamy, Sivasankar, et al.
Publicado: (2014)

Genotypic and Phenotypic Characterization of P23H Line 1 Rat Model
por: Orhan, Elise, et al.
Publicado: (2015)

Spectrum of Cav1.4 dysfunction in congenital stationary night blindness type 2()
por: Burtscher, Verena, et al.
Publicado: (2014)

Group I mGluRs in Therapy and Diagnosis of Parkinson’s Disease: Focus on mGluR5 Subtype
por: Azam, Shofiul, et al.
Publicado: (2022)

AAV-Mediated Transduction and Targeting of Retinal Bipolar Cells with Improved mGluR6 Promoters in Rodents and Primates
por: Lu, Q, et al.
Publicado: (2016)

TRPM1 Mutations are the Most Common Cause of Autosomal Recessive Congenital Stationary Night Blindness (CSNB) in the Palestinian and Israeli Populations
por: AlTalbishi, Alaa, et al.
Publicado: (2019)

Optic Atrophy and Inner Retinal Thinning in CACNA1F-Related Congenital Stationary Night Blindness
por: Leahy, Kate E, et al.
Publicado: (2021)

Metabotropic glutamate receptors (mGluRs) in epileptogenesis: an update on abnormal mGluRs signaling and its therapeutic implications
por: Huang, Leyi, et al.
Publicado: (2023)

Impact of the COVID-19 lockdown on basic science research in ophthalmology: the experience of a highly specialized research facility in France
por: Nassisi, Marco, et al.
Publicado: (2020)

mGluR5, CB1 and neuroprotection
por: Carvalho, Toniana G., et al.
Publicado: (2016)

The orthosteric agonist 2-chloro-5-hydroxyphenylglycine activates mGluR5 and mGluR1 with similar efficacy and potency
por: Kammermeier, Paul J
Publicado: (2012)

The Changes in mGluR2 and mGluR7 Expression in Rat Medial Vestibular Nucleus and Flocculus Following Unilateral Labyrinthectomy
por: Zhou, Wen, et al.
Publicado: (2013)

Pretreatment with mGluR2 or mGluR3 Agonists Reduces Apoptosis Induced by Hypoxia-Ischemia in Neonatal Rat Brains
por: Bratek - Gerej, Ewelina, et al.
Publicado: (2021)

Prevalence of ABCA4 Deep-Intronic Variants and Related Phenotype in An Unsolved “One-Hit” Cohort with Stargardt Disease
por: Nassisi, Marco, et al.
Publicado: (2019)

Targeting ON-bipolar cells by AAV gene therapy stably reverses LRIT3-congenital stationary night blindness
por: Miyadera, Keiko, et al.
Publicado: (2022)

mGluR5 Is Substitutable for mGluR1 in Cerebellar Purkinje Cells for Motor Coordination, Developmental Synapse Elimination, and Motor Learning
por: Harbers, Maria, et al.
Publicado: (2022)

Monocular Deprivation Affects Visual Cortex Plasticity Through cPKCγ-Modulated GluR1 Phosphorylation in Mice
por: Zhang, Yunxia, et al.
Publicado: (2020)

Investigating the role of mGluR2 versus mGluR3 in antipsychotic-like effects, sleep-wake architecture and network oscillatory activity using novel Han Wistar rats lacking mGluR2 expression
por: Wood, Christian M., et al.
Publicado: (2018)

New Editing Tools for Gene Therapy in Inherited Retinal Dystrophies
por: Pulman, Juliette, et al.
Publicado: (2022)

mGluR-Dependent Synaptic Plasticity in Drug-Seeking
por: Bellone, Camilla, et al.
Publicado: (2012)

PET imaging of mGluR5 in Alzheimer’s disease
por: Mecca, Adam P., et al.
Publicado: (2020)

Extinction-Dependent Alterations in Corticostriatal mGluR2/3 and mGluR7 Receptors following Chronic Methamphetamine Self-Administration in Rats
por: Schwendt, Marek, et al.
Publicado: (2012)

Opposite Effects of mGluR1a and mGluR5 Activation on Nucleus Accumbens Medium Spiny Neuron Dendritic Spine Density
por: Gross, Kellie S., et al.
Publicado: (2016)

Transgenerational deep sequencing revealed hypermethylation of hippocampal mGluR1 gene with altered mRNA expression of mGluR5 and mGluR3 associated with behavioral changes in Sprague Dawley rats with history of prolonged febrile seizure
por: Alese, Oluwole Ojo, et al.
Publicado: (2019)

Target validation: Weak selectivity of LY341495 for mGluR2 over mGluR4 makes glutamate a less selective agonist
por: McCullock, Tyler W., et al.
Publicado: (2019)

Two routes to autism phenotypes via mGluR5
Publicado: (2012)

Translational Concepts of mGluR5 in Synaptic Diseases of the Brain
por: Piers, Thomas M., et al.
Publicado: (2012)

Therapeutic potential of mGluR5 targeting in Alzheimer's disease
por: Kumar, Anil, et al.
Publicado: (2015)

mGluR5 hypofunction is integral to glutamatergic dysregulation in schizophrenia
por: Wang, Hoau-Yan, et al.
Publicado: (2018)

Neuromodulation by mGluRs in Sound Localization Circuits in the Auditory Brainstem
por: Goel, Nupur, et al.
Publicado: (2020)

Reduced mGluR5 Activity Modulates Mitochondrial Function
por: Gonzalez-Lozano, Miguel A., et al.
Publicado: (2021)

Selective Recruitment of Presynaptic and Postsynaptic Forms of mGluR-LTD
por: Sanderson, Thomas M., et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_naajbrm3ft5d6lq1embb780jbd