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Interferon system deficiencies exacerbating severe pandemic virus infections

Pandemics are caused by novel pathogens to which pre-existing antibody immunity is lacking. Under these circumstances, the body must rely on innate interferon-mediated defenses to limit pathogen replication and allow development of critical humoral protection. Here, we highlight studies on disease s...

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Detalles Bibliográficos
Autores principales: Stertz, Silke, Hale, Benjamin G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Ltd. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7980109/
https://www.ncbi.nlm.nih.gov/pubmed/33757684
http://dx.doi.org/10.1016/j.tim.2021.03.001