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Genetic Composition and Autoantibody Titers Model the Probability of Detecting C-Peptide Following Type 1 Diabetes Diagnosis

We and others previously demonstrated that a type 1 diabetes genetic risk score (GRS) improves the ability to predict disease progression and onset in at-risk subjects with islet autoantibodies. Here, we hypothesized that GRS and islet autoantibodies, combined with age at onset and disease duration,...

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Detalles Bibliográficos
Autores principales: Williams, MacKenzie D., Bacher, Rhonda, Perry, Daniel J., Grace, C. Ramsey, McGrail, Kieran M., Posgai, Amanda L., Muir, Andrew, Chamala, Srikar, Haller, Michael J., Schatz, Desmond A., Brusko, Todd M., Atkinson, Mark A., Wasserfall, Clive H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Diabetes Association 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7980194/
https://www.ncbi.nlm.nih.gov/pubmed/33419759
http://dx.doi.org/10.2337/db20-0937