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The human bone marrow harbors a CD45(−) CD11B(+) cell progenitor permitting rapid microglia‐like cell derivative approaches

Microglia, the immune sentinel of the central nervous system (CNS), are generated from yolk sac erythromyeloid progenitors that populate the developing CNS. Interestingly, a specific type of bone marrow‐derived monocyte is able to express a yolk sac microglial signature and populate CNS in disease....

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Detalles Bibliográficos
Autores principales: Bruzelius, Andreas, Hidalgo, Isabel, Boza‐Serrano, Antonio, Hjelmér, Anna‐Giorgia, Tison, Amelie, Deierborg, Tomas, Bengzon, Johan, Ramos‐Moreno, Tania
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7980218/
https://www.ncbi.nlm.nih.gov/pubmed/33295698
http://dx.doi.org/10.1002/sctm.20-0127