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The human bone marrow harbors a CD45(−) CD11B(+) cell progenitor permitting rapid microglia‐like cell derivative approaches
Microglia, the immune sentinel of the central nervous system (CNS), are generated from yolk sac erythromyeloid progenitors that populate the developing CNS. Interestingly, a specific type of bone marrow‐derived monocyte is able to express a yolk sac microglial signature and populate CNS in disease....
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley & Sons, Inc.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7980218/ https://www.ncbi.nlm.nih.gov/pubmed/33295698 http://dx.doi.org/10.1002/sctm.20-0127 |