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Disruption of neonatal Purkinje cell function underlies injury-related learning deficits

It is hypothesized that perinatal cerebellar injury leads to long-term functional deficits due to circuit dysmaturation. Using a novel integration of GCaMP6f fiber photometry with automated measurement of cerebellar behavior using the ErasmusLadder, we causally link cerebellar injury to altered Purk...

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Detalles Bibliográficos
Autores principales: Sathyanesan, Aaron, Kratimenos, Panagiotis, Gallo, Vittorio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7980280/
https://www.ncbi.nlm.nih.gov/pubmed/33688045
http://dx.doi.org/10.1073/pnas.2017876118