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Neurodegenerative phosphoprotein signaling landscape in models of SCA3

Spinocerebellar ataxia type 3 (SCA3) is a rare neurodegenerative disorder resulting from an aberrant expansion of a polyglutamine stretch in the ataxin-3 protein and subsequent neuronal death. The underlying intracellular signaling pathways are currently unknown. We applied the Reverse-phase Protein...

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Detalles Bibliográficos
Autores principales: Sowa, Anna S., Popova, Taissia G., Harmuth, Tina, Weber, Jonasz J., Pereira Sena, Priscila, Schmidt, Jana, Hübener-Schmid, Jeannette, Schmidt, Thorsten
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7980345/
https://www.ncbi.nlm.nih.gov/pubmed/33741019
http://dx.doi.org/10.1186/s13041-020-00723-0