Cargando…
Neurodegenerative phosphoprotein signaling landscape in models of SCA3
Spinocerebellar ataxia type 3 (SCA3) is a rare neurodegenerative disorder resulting from an aberrant expansion of a polyglutamine stretch in the ataxin-3 protein and subsequent neuronal death. The underlying intracellular signaling pathways are currently unknown. We applied the Reverse-phase Protein...
Autores principales: | Sowa, Anna S., Popova, Taissia G., Harmuth, Tina, Weber, Jonasz J., Pereira Sena, Priscila, Schmidt, Jana, Hübener-Schmid, Jeannette, Schmidt, Thorsten |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7980345/ https://www.ncbi.nlm.nih.gov/pubmed/33741019 http://dx.doi.org/10.1186/s13041-020-00723-0 |
Ejemplares similares
-
Mitochondrial Dysfunction in Spinocerebellar Ataxia Type 3 Is Linked to VDAC1 Deubiquitination
por: Harmuth, Tina, et al.
Publicado: (2022) -
From Pathways to Targets: Understanding the Mechanisms behind Polyglutamine Disease
por: Weber, Jonasz Jeremiasz, et al.
Publicado: (2014) -
KPNB1 modulates the Machado–Joseph disease protein ataxin-3 through activation of the mitochondrial protease CLPP
por: Abeditashi, Mahkameh, et al.
Publicado: (2022) -
Ataxin-3, The Spinocerebellar Ataxia Type 3 Neurodegenerative Disorder Protein, Affects Mast Cell Functions
por: Sowa, Anna S., et al.
Publicado: (2022) -
Killing Two Angry Birds with One Stone: Autophagy Activation by Inhibiting Calpains in Neurodegenerative Diseases and Beyond
por: Weber, Jonasz Jeremiasz, et al.
Publicado: (2019)