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Dual-process brain mitochondria isolation preserves function and clarifies protein composition

The brain requires continuously high energy production to maintain ion gradients and normal function. Mitochondria critically undergird brain energetics, and mitochondrial abnormalities feature prominently in neuropsychiatric disease. However, many unique aspects of brain mitochondria composition an...

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Detalles Bibliográficos
Autores principales: Noterman, Maria F., Chaubey, Kalyani, Lin-Rahardja, Kristi, Rajadhyaksha, Anjali M., Pieper, Andrew A., Taylor, Eric B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7980376/
https://www.ncbi.nlm.nih.gov/pubmed/33836587
http://dx.doi.org/10.1073/pnas.2019046118