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Super-resolution mapping of cellular double-strand break resection complexes during homologous recombination

Homologous recombination (HR) is a major pathway for repair of DNA double-strand breaks (DSBs). The initial step that drives the HR process is resection of DNA at the DSB, during which a multitude of nucleases, mediators, and signaling proteins accumulates at the damage foci in a manner that remains...

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Detalles Bibliográficos
Autores principales: Whelan, Donna R., Rothenberg, Eli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7980414/
https://www.ncbi.nlm.nih.gov/pubmed/33707212
http://dx.doi.org/10.1073/pnas.2021963118