Neuroprotective effect of mitochondrial translocator protein ligand in a mouse model of tauopathy

BACKGROUND: The translocator protein (TSPO) has been identified as a positron emission tomography (PET)-visible biomarker of inflammation and promising immunotherapeutic target for the treatment of Alzheimer’s disease (AD). While TSPO ligands have been shown to reduce the accumulation of the toxic A...

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Detalles Bibliográficos
Autores principales: Fairley, Lauren H., Sahara, Naruhiko, Aoki, Ichio, Ji, Bin, Suhara, Tetsuya, Higuchi, Makoto, Barron, Anna M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7980620/
https://www.ncbi.nlm.nih.gov/pubmed/33740987
http://dx.doi.org/10.1186/s12974-021-02122-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7980620/
https://www.ncbi.nlm.nih.gov/pubmed/33740987
http://dx.doi.org/10.1186/s12974-021-02122-1

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