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Neuroprotective effect of mitochondrial translocator protein ligand in a mouse model of tauopathy

BACKGROUND: The translocator protein (TSPO) has been identified as a positron emission tomography (PET)-visible biomarker of inflammation and promising immunotherapeutic target for the treatment of Alzheimer’s disease (AD). While TSPO ligands have been shown to reduce the accumulation of the toxic A...

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Detalles Bibliográficos
Autores principales:	Fairley, Lauren H., Sahara, Naruhiko, Aoki, Ichio, Ji, Bin, Suhara, Tetsuya, Higuchi, Makoto, Barron, Anna M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7980620/ https://www.ncbi.nlm.nih.gov/pubmed/33740987 http://dx.doi.org/10.1186/s12974-021-02122-1

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