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Accumulation of alpha-synuclein within the liver, potential role in the clearance of brain pathology associated with Parkinson’s disease

Alpha-synuclein (α-syn) aggregation is the hallmark pathological lesion in brains of patients with Parkinson’s disease (PD) and related neurological disorders characterized as synucleinopathies. Accumulating evidence now indicates that α-syn deposition is also present within the gut and other periph...

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Detalles Bibliográficos
Autores principales: Reyes, Juan F., Ekmark-Léwen, Sara, Perdiki, Marina, Klingstedt, Therése, Hoffmann, Alana, Wiechec, Emilia, Nilsson, Per, Nilsson, K. Peter R., Alafuzoff, Irina, Ingelsson, Martin, Hallbeck, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7980682/
https://www.ncbi.nlm.nih.gov/pubmed/33743820
http://dx.doi.org/10.1186/s40478-021-01136-3