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Intranasal delivery of plasmids expressing bovine herpesvirus 1 gB/gC/gD proteins by polyethyleneimine magnetic beads activates long-term immune responses in mice

BACKGROUND: DNA vaccine is one of the research hotspots in veterinary vaccine development. Several advantages, such as cost-effectiveness, ease of design and production, good biocompatibility of plasmid DNA, attractive biosafety, and DNA stability, are found in DNA vaccines. METHODS: In this study,...

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Detalles Bibliográficos
Autores principales: Liu, Xing-Bo, Yu, Guo-Wei, Gao, Xin-Yu, Huang, Jin-Long, Qin, Li-Ting, Ni, Hong-Bo, Lyu, Chuang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7981393/
https://www.ncbi.nlm.nih.gov/pubmed/33743745
http://dx.doi.org/10.1186/s12985-021-01536-w