NTRK2 Fusion driven pediatric glioblastoma: Identification of oncogenic Drivers via integrative Genome and transcriptome profiling

This is the first report of a NACC2‐NTRK2 fusion in a histological glioblastoma. Oncogenomic analysis revealed this actionable fusion oncogene in a pediatric cerebellar glioblastoma, which would not have been identified through routine diagnostics, demonstrating the value of clinical genome profilin...

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Detalles Bibliográficos
Autores principales: Britton, Heidi M., Levine, Adrian B., Shen, Yaoqing, Mungall, Karen, Serrano, Jonathan, Snuderl, Matija, Pleasance, Erin, Jones, Steven J. M., Laskin, Janessa, Marra, Marco A., Rassekh, Shahrad R., Deyell, Rebecca, Yip, Stephen, Cheng, Sylvia, Dunham, Chris
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Case Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7981675/
https://www.ncbi.nlm.nih.gov/pubmed/33768871
http://dx.doi.org/10.1002/ccr3.3804

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7981675/
https://www.ncbi.nlm.nih.gov/pubmed/33768871
http://dx.doi.org/10.1002/ccr3.3804

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