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Is targeting autophagy mechanism in cancer a good approach? The possible double-edge sword effect

Autophagy is a conserved cellular process required to maintain homeostasis. The hallmark of autophagy is the formation of a phagophore that engulfs cytosolic materials for degradation and recycling to synthesize essential components. Basal autophagy is constitutively active under normal conditions a...

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Detalles Bibliográficos
Autores principales: Lim, Su Min, Mohamad Hanif, Ezanee Azlina, Chin, Siok-Fong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7981910/
https://www.ncbi.nlm.nih.gov/pubmed/33743781
http://dx.doi.org/10.1186/s13578-021-00570-z