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Is targeting autophagy mechanism in cancer a good approach? The possible double-edge sword effect
Autophagy is a conserved cellular process required to maintain homeostasis. The hallmark of autophagy is the formation of a phagophore that engulfs cytosolic materials for degradation and recycling to synthesize essential components. Basal autophagy is constitutively active under normal conditions a...
Autores principales: | Lim, Su Min, Mohamad Hanif, Ezanee Azlina, Chin, Siok-Fong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7981910/ https://www.ncbi.nlm.nih.gov/pubmed/33743781 http://dx.doi.org/10.1186/s13578-021-00570-z |
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