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TOX as a potential target for immunotherapy in lymphocytic malignancies

TOX (thymocyte selection-associated HMG BOX) is a member of a family of transcriptional factors that contain the highly conserved high mobility group box (HMG-box) region. Increasing studies have shown that TOX is involved in maintaining tumors and promoting T cell exhaustion. In this review, we sum...

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Detalles Bibliográficos
Autores principales: Liang, Chaofeng, Huang, Shuxin, Zhao, Yujie, Chen, Shaohua, Li, Yangqiu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7981945/
https://www.ncbi.nlm.nih.gov/pubmed/33743809
http://dx.doi.org/10.1186/s40364-021-00275-y