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The effects of model complexity and size on metabolic flux distribution and control: case study in Escherichia coli
BACKGROUND: Significant efforts have been made in building large-scale kinetic models of cellular metabolism in the past two decades. However, most kinetic models published to date, remain focused around central carbon pathways or are built around ad hoc reduced models without clear justification on...
Autores principales: | Hameri, Tuure, Fengos, Georgios, Hatzimanikatis, Vassily |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7981984/ https://www.ncbi.nlm.nih.gov/pubmed/33743594 http://dx.doi.org/10.1186/s12859-021-04066-y |
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