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Pharmacogenomics biomarkers for personalized methadone maintenance treatment: The mechanism and its potential use

Methadone has a wide pharmacokinetic interindividual variability, resulting in unpredicted treatment response. Pharmacogenomic biomarkers seem promising for personalized methadone maintenance treatment. The evidence supports the use of ABCB1 single-nucleotide polymorphism (SNP) 1236C>T with genot...

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Detalles Bibliográficos
Autor principal: Ramli, Fitri Fareez
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Association of Basic Medical Sciences of Federation of Bosnia and Herzegovina 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7982063/
https://www.ncbi.nlm.nih.gov/pubmed/32841585
http://dx.doi.org/10.17305/bjbms.2020.4897