Functional metabolomics reveal the role of AHR/GPR35 mediated kynurenic acid gradient sensing in chemotherapy-induced intestinal damage

Intestinal toxicity induced by chemotherapeutics has become an important reason for the interruption of therapy and withdrawal of approved agents. In this study, we demonstrated that chemotherapeutics-induced intestinal damage were commonly characterized by the sharp upregulation of tryptophan (Trp)...

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Detalles Bibliográficos
Autores principales: Wang, Di, Li, Danting, Zhang, Yuxin, Chen, Jie, Zhang, Ying, Liao, Chuyao, Qin, Siyuan, Tian, Yuan, Zhang, Zunjian, Xu, Fengguo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7982426/
https://www.ncbi.nlm.nih.gov/pubmed/33777681
http://dx.doi.org/10.1016/j.apsb.2020.07.017

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7982426/
https://www.ncbi.nlm.nih.gov/pubmed/33777681
http://dx.doi.org/10.1016/j.apsb.2020.07.017

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