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A novel SIRT6 activator ameliorates neuroinflammation and ischemic brain injury via EZH2/FOXC1 axis

Ischemic stroke is the second leading cause of death worldwide with limited medications and neuroinflammation was recognized as a critical player in the progression of stroke, but how to control the overactive neuroinflammation is still a long-standing challenge. Here, we designed a novel SIRT6 acti...

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Detalles Bibliográficos
Autores principales: He, Tailin, Shang, Jialin, Gao, Chenglong, Guan, Xin, Chen, Yingyi, Zhu, Liwen, Zhang, Luyong, Zhang, Cunjin, Zhang, Jian, Pang, Tao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7982432/
https://www.ncbi.nlm.nih.gov/pubmed/33777677
http://dx.doi.org/10.1016/j.apsb.2020.11.002