Discovery of New α-Glucosidase Inhibitors: Structure-Based Virtual Screening and Biological Evaluation

α-Glycosidase inhibitors could inhibit the digestion of carbohydrates into glucose and promote glucose conversion, which have been used for the treatment of type 2 diabetes. In the present study, 52 candidates of α-glycosidase inhibitors were selected from commercial Specs compound library based on...

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Detalles Bibliográficos
Autores principales: Liu, Shan-Kui, Hao, Haifang, Bian, Yuan, Ge, Yong-Xi, Lu, Shengyuan, Xie, Hong-Xu, Wang, Kai-Ming, Tao, Hongrui, Yuan, Chao, Zhang, Juan, Zhang, Jie, Jiang, Cheng-Shi, Zhu, Kongkai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7982526/
https://www.ncbi.nlm.nih.gov/pubmed/33763406
http://dx.doi.org/10.3389/fchem.2021.639279

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7982526/
https://www.ncbi.nlm.nih.gov/pubmed/33763406
http://dx.doi.org/10.3389/fchem.2021.639279

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