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Significant Redox Insensitivity of the Functions of the SARS-CoV Spike Glycoprotein: COMPARISON WITH HIV ENVELOPE

The capacity of the surface glycoproteins of enveloped viruses to mediate virus/cell binding and membrane fusion requires a proper thiol/disulfide balance. Chemical manipulation of their redox state using reducing agents or free sulfhydryl reagents affects virus/cell interaction. Conversely, natural...

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Detalles Bibliográficos
Autores principales: Lavillette, Dimitri, Barbouche, Rym, Yao, Yongxiu, Boson, Bertrand, Cosset, François-Loïc, Jones, Ian M., Fenouillet, Emmanuel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: ASBMB. Currently published by Elsevier Inc; originally published by American Society for Biochemistry and Molecular Biology. 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7982606/
https://www.ncbi.nlm.nih.gov/pubmed/16418166
http://dx.doi.org/10.1074/jbc.M512529200