Multigene PCR using both cfDNA and cfRNA in the supernatant of pleural effusion achieves accurate and rapid detection of mutations and fusions of driver genes in patients with advanced NSCLC

BACKGROUND: Pleural effusion from patients with advanced non‐small cell lung cancer (NSCLC) has been proved valuable for molecular analysis, especially when the tissue sample not available. However, simultaneous detection of multiple driver gene alterations especially the fusions is still challengin...

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Detalles Bibliográficos
Autores principales: Chen, Xuejing, Li, Kun, Liu, Zichen, Gai, Fei, Zhu, Guanshan, Lu, Shun, Che, Nanying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Clinical Cancer Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7982639/
https://www.ncbi.nlm.nih.gov/pubmed/33656807
http://dx.doi.org/10.1002/cam4.3769

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7982639/
https://www.ncbi.nlm.nih.gov/pubmed/33656807
http://dx.doi.org/10.1002/cam4.3769

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