Phosphodiesterase-4 Inhibition in Psoriasis

Psoriasis is a chronic immune-mediated inflammatory disorder. Phosphodiesterase-4 (PDE-4) is an enzyme that mediates inflammatory responses and plays a role in psoriasis pathogenesis. PDE-4 degrades its substrate cyclic adenosine monophosphate (cAMP) to adenosine monophosphate (AMP), which subsequen...

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Detalles Bibliográficos
Autores principales: Milakovic, Milica, Gooderham, Melinda J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7982714/
https://www.ncbi.nlm.nih.gov/pubmed/33763335
http://dx.doi.org/10.2147/PTT.S303634

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7982714/
https://www.ncbi.nlm.nih.gov/pubmed/33763335
http://dx.doi.org/10.2147/PTT.S303634

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