Arrest in the Progression of Type 1 Diabetes at the Mid-Stage of Insulitic Autoimmunity Using an Autoantigen-Decorated All-trans Retinoic Acid and Transforming Growth Factor Beta-1 Single Microparticle Formulation

Type 1 diabetes (T1D) is a disorder of impaired glucoregulation due to lymphocyte-driven pancreatic autoimmunity. Mobilizing dendritic cells (DC) in vivo to acquire tolerogenic activity is an attractive therapeutic approach as it results in multiple and overlapping immunosuppressive mechanisms. Deli...

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Detalles Bibliográficos
Autores principales: Phillips, Brett E., Garciafigueroa, Yesica, Engman, Carl, Liu, Wen, Wang, Yiwei, Lakomy, Robert J., Meng, Wilson S., Trucco, Massimo, Giannoukakis, Nick
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7982719/
https://www.ncbi.nlm.nih.gov/pubmed/33763059
http://dx.doi.org/10.3389/fimmu.2021.586220

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7982719/
https://www.ncbi.nlm.nih.gov/pubmed/33763059
http://dx.doi.org/10.3389/fimmu.2021.586220

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