LINC01116 Promotes Doxorubicin Resistance in Osteosarcoma by Epigenetically Silencing miR-424-5p and Inducing Epithelial-Mesenchymal Transition

Background: Development of resistance to doxorubicin-based chemotherapy limits its curative effect in osteosarcoma. In the current study, we focused on investigating the mechanisms underlying the development of doxorubicin resistance in osteosarcoma. Methods: The human osteosarcoma cell line MG-63 a...

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Detalles Bibliográficos
Autores principales: Li, Ran, Ruan, Qing, Zheng, Jia, Zhang, Butian, Yang, Hongliang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7982720/
https://www.ncbi.nlm.nih.gov/pubmed/33762953
http://dx.doi.org/10.3389/fphar.2021.632206

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7982720/
https://www.ncbi.nlm.nih.gov/pubmed/33762953
http://dx.doi.org/10.3389/fphar.2021.632206

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