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Protocol for purification and identification of MHC class I immunopeptidome from cancer cell lines

Major histocompatibility complexes (MHC) play a critical role in immunity by presenting peptides on the cell surface for T cell recognition. Identification of these peptides can be valuable to develop vaccines or immunotherapeutic strategies for infectious diseases and cancers. Mass spectrometry is...

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Detalles Bibliográficos
Autores principales: Mohan, Sonali V., Datta, Keshava K., Ziegman, Rebekah, Smith, Corey, Gowda, Harsha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7982746/
https://www.ncbi.nlm.nih.gov/pubmed/33778779
http://dx.doi.org/10.1016/j.xpro.2021.100385