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Protocol for in vitro skin fibrosis model to screen the biological effects of antifibrotic compounds
Controversies remain over the standard procedures for the modeling of skin fibrosis and its use in in vitro testing of different drugs. Here, we report a reproducible protocol for producing a skin fibrosis model using human dermal fibroblasts seeded in collagen hydrogel. Detailed procedures for the...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7982747/ https://www.ncbi.nlm.nih.gov/pubmed/33778781 http://dx.doi.org/10.1016/j.xpro.2021.100387 |