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Purification of micronuclei from cultured cells by flow cytometry

Micronuclei are aberrant nuclear compartments that form when chromosomes or chromosome fragments fail to incorporate into a primary nucleus during mitotic exit. Ruptures at the micronuclear envelope are associated with DNA damage and activation of immune sensing pathways. To gain insights into these...

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Detalles Bibliográficos
Autores principales: Toufektchan, Eléonore, Maciejowski, John
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7982749/
https://www.ncbi.nlm.nih.gov/pubmed/33778777
http://dx.doi.org/10.1016/j.xpro.2021.100378